Bioinformatics analysis for oncolytic viruses
- Identify similar sequence
Use
BLAST
algorithms to identify similar nucleotide or amino acid sequences in a variety of custom DBOVI databases.
- Align sequences
Use
ClustalW
or
MUSCLE
to align nucleotide or amino acid sequences.
- Identify point mutations
Identify protein sequences that have a specific amino acid at a specific position.
- Analyze sequence variation
Compute the extent of variation at each position of virus nucleotide or amino acid sequences uploaded to the DBOVI analysis tool or selected from the DBOVI database.
- Phylogenetic anaysis
Generate phylogenetic tree with commonly used methods provided by the
ClustalW2
program or
MEGA
to align nucleotide or amino acid sequences.
Since March 16, 2015 by LCBB
